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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19e6e8e2017b6e9bb94d47947ecba3f3364d4ca2f38d4a63f1b39f863e49f283' 
  AND token = 'wpXq4HphdeZyf4yd2CHgI2DeS/rwIrYXqDsWoL5RxmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}