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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20d2a4f23327a42315dea1794f99d3b50aa647dd0482c55a05f89b1786694943' 
  AND token = 'FXOIsGXhOAsPd0haDNAulZqm+tko47CdsXL1EMhdlQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}