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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f9e563dd81e440728498526b932e0647ad40575ebaf0ef1640df054ff8a7f3' 
  AND token = 'mu57yikM1kOSdyre2qhwUGMBH8pa0sLnTq+EHWRDUAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}