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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34f00d0de6044e10a71dbfedc66abda01c423554d92173926141af35c4e75a49' 
  AND token = '75D3C6I6tHO7OgI7OMxm8e5OIu/7J7CugKNFtQfoFBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}