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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae7a14b340bab368b1e2dc5d4661a9fdee6d22f374541d1293a4f3256cc8bb1d' 
  AND token = 'pAVyJWKrvJAiGMpfUcJS/y3nB66T4bL3413urSXC0Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}