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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bec4c0d44d1cd6f53badc32d92d0e2a578baf11f9dbda18d92a85de93aabf4d' 
  AND token = 'kfLLyCjNizmAIB+0gE4a6M/39K9oQ2qLf/2yWSIhj1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}