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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6caadee80678d6646e98dae0aaa727063673109a58c5aa8480442461a9535af' 
  AND token = 'Zm7tXZQ1je692pu1aDEi0SsrQEenchL+7XgoTtz3wPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}