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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79eac509863dc3bb8d6c0e7117a15c3ca5ebd89f1b869991881d8536376578e0' 
  AND token = 'dCOlNfK38z+SC7wMUFi+rGwtXwsdfyKlEp5YdXRHepg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}