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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f426df5b753b5dfa5b49d24ef06eb36820e3f4a90dfa3b314a56828341936f' 
  AND token = 'oEaj8VCSBc9ETmWhdzQ9ceBzfV0qUheLwtVV6V1ES5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}