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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab1b9b71aeca53b3dd49a107a54e6ab22787e2e7ebef179a7198bf1f2c66893f' 
  AND token = 'YkSA2CNpGx4CV2fIUDLz/eoYdFGX0BwSHH2+RKeT/7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}