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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52f33940b496885d7993e5d08d12b374e81609739273fa5d6ee8c205b6b46a8' 
  AND token = 'G3VERnXyZRo1X+raOKCLZEk7egF2iz636C9TJbcF0vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}