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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164a07d2ef7e19063176f66774bcfe1c4d8f336b4fd88be208f9fd21a090ec75' 
  AND token = 'EQgqdGrJRzpuGSy0Cwvu7DAF6qcAQwk9nHom97olbHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}