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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d08ca40d946ae7f60b1f4b8089037318a9f7aa87a3abc12ca4f1e99edae047' 
  AND token = 'dl36+L6AWaDy7+YfJwXM/ND8FUdsquCL9CSoSbCUWAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}