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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb8b36f17011d5fec13de98772800d0ece47716bb1fb1d5fd1e1ba524cdd11b' 
  AND token = 'c1Z43JCsDRnaXB/QoOioa3JEynzSCmAM+nmTf4PXr3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}