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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0121c2606572f868e3e44ca70c4e190b3272b6481cc6cbe31e41e12e3e7bb03a' 
  AND token = 'CRa5akWm4WY/YzvgCxzWwlko84r23pp/Go+9ImlL2iE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}