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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b50ca6d4b072eee765c4fb6dc518f201a7d143c344ecead3451b2afd0544d5a' 
  AND token = 'Dy/NC2QY/RH+yT2Cu9YNZ1AKJXZj4itGFIxs/wSUNlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}