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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1cfdb4186ef824ebfe55514c0d816e08f124d1f50737843c40f983427004c8' 
  AND token = '/H3U//uWnz92+hPIIvVF9yCq0T8B9WarrPOiMio4L0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}