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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2600af92732fb85544c3811af0b48b25bc915753be8b20a95cbc6d6915ea724' 
  AND token = 'egd7SJJWdbHa+WtEU4cog6FQKpex3qFZMJsiRiVHVqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}