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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f108f35f28b1c9692a625ea4592b9272d39d8ef7841109bf928aa15c8e64f1' 
  AND token = 'QbdpW0ivgmBot+Q5ZlYtkzPy50CfSAkejs2RfKKMPV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}