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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c49b2e0c6e866e98a7c4c592a39155df2907b95f782db462ff7f75af5b12188' 
  AND token = 'TGQ2sJ8Il+uY4oYcZ665eFRnzP0n0aoWWWYAv7kK1hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}