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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3080935b13f14c0d828551d70cb4c850e087fa1ec170339d22e0dec6397dfe' 
  AND token = 'bABEkl6rnX4KF9sOhqQvCPI8rd26CuntQIoiUaV35So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}