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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa32efa6252411f1a1cfb9b7d10957e240bc7aeec28d093d979fa9dc380354de' 
  AND token = 'ITrNtcinFhXpC2gXaxAQbgnhcE0C1X9iPxkMY/+Ybdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}