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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a168bf38c7764e239b33f71bf29b414d6fa636d7fc797d05d49fb17a4c9689a7' 
  AND token = 'Z/9DQotMaYBkD4Mr6JXOrwnj40t/TaL0aAgSNw4uo0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}