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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3d6c9402412c95599abf98329a2a1a39cfa8e7746678ba9de7895c917927d7' 
  AND token = 'yqkao7UpCxSY4CjlotGD3trvQB8hQRJQhe/9Y5e4RDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}