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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e09e870e5f76da75f8ed647a654d0506be4b48b9fbb973ca2498ed59582a089' 
  AND token = 'mYiuzWTYTA46GZolg2ME+sKrcZRIKEFRWOlMqY4qW5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}