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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8225511d1d2408b34cda9fc0b981c45938e8d6eb36d3cfaca302a5dd24377c6' 
  AND token = '14a7Oa29FcHoaVdfjLYrShTwc2/Arf2wIrt7Pa714A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}