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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90088a1a466677203abcbdb7945dab98598f88ba02e9dfbeabebadbf44b4a4b' 
  AND token = 'DsP8Hhu3dSPDqtXeSlrXv/TJTm8X1Zwtbda+HxwM2AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}