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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd725f5272a15c62a7b04b27fc805d03b5500e46d0036c9e1533fd8886accab03' 
  AND token = 'HGBRkpXeqStR3rpPJBuwqseCITd/XECsnxPDa8nZEvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}