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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ed06b5a379256537153ade78e6c28e7a233812afecd3623470fb480b6902dc' 
  AND token = '8bcEzmLgDl1x2GSGvOaAChKtpYi5npAL4CrXl8DSkiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}