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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b13bb8d2ea0afd0d38672b57cfeb8b8c4e4178efc1f1cfdc9b00317595cbf80' 
  AND token = 'FdQAv7QIiK4vrh2pNbHQqcNkQ1UVkDnxeEGxr8nTnuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}