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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8163f6c7533dc3022e021712d15e70cdce96a8d2bd5126f08ee41ee135e38a70' 
  AND token = 'HDFbL79ueZVxWdKgL8mlaFb8l4fOMAp5twDvCIGTNeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}