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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be5300639d0bcb93e46e842cea1ce0a3f3184ffbab78bf41e2f9e005dcddf28' 
  AND token = 'lYPDElS7XibX+wDHsuhTM29e/HHedMPoWuru5O9sT8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}