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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2af3f39a669eb313451f1d40366b053c466626cb13bc4e1ab9356b7843e017' 
  AND token = 'kNrPiZeAjxlsmBt+VKpzOrHUHqMdjyrEcQ0NWXyjj/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}