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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19516cda60c96298247a503c313d27d2e437722a55718fd160cf396984e2d6b8' 
  AND token = 'cTiMPKjkfXKGRTA2FGGtp44wDTutLSqfSiDWOexdxk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}