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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe25809667cb07701357cfa1782abbca8e897707098c953d04fb1274e3e3577' 
  AND token = 'SIoD3edQTo9a8B2yY15S30FWG1uc3pT1lpHH/2EFZQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}