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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f47716e573f234401318c146fba23023c39b05055921f9793833c58d20952d7' 
  AND token = 'bS1vTPOLSLVTUHAP7R/TNuU7XoDMjym591rR2HORicQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}