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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2fb0725351c8493a9ba3fdcc2fc597b64252b91b7bb5d2847a6c9c5b52f193' 
  AND token = 'R87dKTA0tysOd/b+R55mSitf+Tb3+qCoPCi7iIL65wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}