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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27caccd68c04fd52952666250f78a18b67a15f64dc0bbeed8ae4bc8bc8e0a300' 
  AND token = 'ESXiLcDKwChJWnysTXCUNh19GbZd6hbv2R90TSO46tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}