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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6206a76b55ec1e5db3e3b9a0727e5a40250f1be4beda57ecf089729a4c9b71d' 
  AND token = 'S0xfuM/6Dc5heqvcEYAoyxqS8rvUxDALlj1eNwnx8yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}