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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9484dc4d9ad5576a3c93d537a801618517d2e6238c8541b40a0a61ef5cc3d81' 
  AND token = 'pXDSAFxmYorXkmvEvJT7WQtHwIsr0rG3l+1GU8WfIGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}