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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1491a04edd8c0a085f13cf14a0358a4f4b9958cd7151634de06a21837d050c' 
  AND token = '3kZvtuRmK3b4J92YkTLgfLuk708pN1v9eAyzy5X7X/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}