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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc49964ebe2de02a0c61d260f0721d068f0465e4143a355e211ba966a9a6224d' 
  AND token = 'MeOriI+2Qt3VWeWwd5XxwXs/dn3aW+USn0Wdeof9nl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}