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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b9015fbb19d8f9b1ddbbf062ded6b799cfdcb2e87a3b73332708bfb38532c2' 
  AND token = '+B/rzalc8XZ6bzJa3CJmHtTVnlMX7dN8Ux3OmJinz3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}