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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '360f734fcb2beb4237966c643c42065020d53e2ae3369819b8453de4e0f75a37' 
  AND token = '7bgGgjZAFRrSCIayLqjdgXxp9IYlGgu4S59fLOCTK4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}