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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e0009c944ab12d6eaaa0b9bf5dcdace70ccf1d6472f84a958798aa0826ce26' 
  AND token = 'ijr2s0bVnFZE94Q1cP+O3PVv0AyKTgIQjnjZi60V1Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}