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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18db9497d0b18bc2aebd5524428b05f090a5660d4e7b6fd7d60bec5563e8002' 
  AND token = 'F9+Dd3h90jXYvkY8QPrtNJUTFjQFl1tc5x8vGYi0KCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}