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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1488edcd52659fd970dbc5f75611e69fe33363e74f4c148e917eb759754f6a80' 
  AND token = '+hdEr3dycufuBxV/8x7OzDjU6+Cmc8QyEqMuLFp+ywQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}