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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0724fe9995b9e3cd90199eda668695cfa5802ed3da93656d9cb76d4dd648458' 
  AND token = 'teh29etYh6hk8CrkWZ2zg/AElZiOYQDBXzVSFWq+VIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}