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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cac3d52049e4b1c82539dea3039767e28ff0530fcedd7ac650769a2ac8be0bf' 
  AND token = 'b3Ba9yLlNav7LOkOc/lKr8S2G1EvETEW5VX+XY0wRqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}