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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300b697048351671e35b033690fc00e5c5e909a7b1611b21a0b58c8637605f7a' 
  AND token = 'Uh6xdSL4SVg58b6MlBBw/jpHjFHs5aOjPSCGa86Yq1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}